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Donor lymphocyte infusion: (DLI) A cancer treatment in which lymphocytes from a bone marrow donor are infused into the person who received the original bone marrow transplant. The goal of donor lymphocyte infusion is to induce a remission of the cancer by a process called the graft-versus-tumor (GVT) effect. Donor lymphocyte infusion is basically meant to boost the GVT effect. The donor lymphocytes, which are T cells, attack and kill residual cancer cells. That is the strategy.
Donor lymphocyte infusion has mainly been used to treat relapsed chronic myelogenous leukemia (CML). Patients with relapsed acute leukemia, chronic lymphocytic leukemia (CLL), myelodysplasia (MDS), Hodgkin disease, non-Hodgkin lymphoma (NHL), and multiple myeloma have also been treated by donor leukocyte infusion.
Policy. Aetna considers donor lymphocyte infusion (DLI) medically necessary for persons who have a prior, medically necessary allogeneic bone marrow or peripheral stem cell ...
Donor lymphocyte infusion: (DLI) A cancer treatment in which lymphocytes from a bone marrow donor are infused into the person who received the original bone marrow transplant.
You might require standard chemotherapy to reduce the amount of cancer you have prior to your donor lymphocyte infusion. Following your donor lymphocyte infusion, you ...
Top of page Abstract. Donor lymphocyte infusion has become established as a salvage therapy for patients with hematological disorders relapsing after allogeneic bone marrow ...
6902 Donor Lymphocyte Infusion ... For patients whose disease persists or recurs after a donor stem cell transplant, a donor lymphocyte infusion (DLI) may be given to try to ...