Down syndrome features: Children with Down syndrome have multiple malformations and mental impairment due to the presence of extra material from chromosome 21.
Among the more common physical features are hypotonia (floppiness), small head with brachycephaly, epicanthic folds across the inside corners of the eyes, upward outward slanting palpebral fissures (eye slits), Brushfield spots in the iris, small mouth, small ears, excessive skin at the nape of the neck, a single transverse palmar crease, and short fifth finger with clinodactyly (incurving). A wide space, often with a deep fissure between the first and second toes, is also common.
There is an increased risk of congenital heart defects (50%); leukemia (
An overview of the features of Down syndrome and some of the medical problems that occur more frequently in people with Down syndrome.
Characteristic Features and Symptoms of Down Syndrome. Despite the variability in Down syndrome, individuals with Down syndrome have a widely recognized characteristic ...
Characteristics of Down Syndrome - The Physical Features of Down Syndrome - Who do they look like? How are they unique or different?
The Features of Down Syndrome A Short Description of the Characteristics Frequently Seen in Down Syndrome. From Kathleen Fergus, former About.com Guide
Down Syndrome Characteristic Features. Despite the variability in Down syndrome, individuals with Down syndrome have a widely recognized characteristic appearance.