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Definition of «Down syndrome features»

Down syndrome featuresDown syndrome featuresDown syndrome featuresDown syndrome features

Down syndrome features: Children with Down syndrome have multiple malformations and mental impairment due to the presence of extra material from chromosome 21.

Among the more common physical features are hypotonia (floppiness), small head with brachycephaly, epicanthic folds across the inside corners of the eyes, upward outward slanting palpebral fissures (eye slits), Brushfield spots in the iris, small mouth, small ears, excessive skin at the nape of the neck, a single transverse palmar crease, and short fifth finger with clinodactyly (incurving). A wide space, often with a deep fissure between the first and second toes, is also common.

There is an increased risk of congenital heart defects (50%); leukemia (

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