EMSY: A novel protein that connects the familial and sporadic forms of breast cancer and ovarian cancer.
Some cases of breast and ovarian cancer are familial and strike women in the same family who have a heritable mutation of a gene called BRCA2 that is involved in DNA repair. However, these genetic cases are in the minority. Most cases of breast and ovarian cancer are sporadic. They occur in women with no family history of these cancers.
In sporadic breast and ovarian cancer, EMSY is amplified and overexpressed. EMSY suppresses the activity of the BRCA2 gene. The overlap between sporadic EMSY amplification and familial BRCA2 deletion implicates a BRCA2 pathway in sporadic breast and ovarian cancer. EMSY connects sporadic breast and ovarian cancer to BRCA2.
PubMed is a service of the U.S. National Library of Medicine that includes over 19 million citations from MEDLINE and other life science journals for biomedical articles ...
EMSY: A novel protein that connects the familial and sporadic forms of breast cancer and ovarian cancer. Some cases of breast and ovarian cancer are familial and strike ...
Confirm Block. Are you sure you want to block this member? This member will not be able to send you messages, comment on your videos/profile or subscribe to your channel.
Rabbit polyclonal to EMSY primary antibody datasheet (ab4580). ... to . Please be aware that this will change the currency in the purchasing process.
Putting Research at The Heart of Primary Care. Our mission is to establish PCRN EMSY as a key contributor to the health and well being of the local populations.