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Definition of «Endostatin»

Endostatin: Endostatin is a piece (a fragment) of a protein, collagen 18, found in all blood vessels. This fragment is normally secreted by tumors. It appears to halt the process of developing new blood vessels (angiogenesis) which is necessary to tumor development. Endostatin may, it is hoped, represent a prototype for a new class of agents with which to treat cancer.

For More Information «Endostatin»

  • endostatin: Definition from Answers.com

    n. A potent, naturally occurring antiangiogenic protein that inhibits the formation of the blood vessels that feed tumors. It is under investigation as a potential ...

  • Endostatin: an endogenous inhibitor of angiogenesi... [Cell ...

    Abstract. We previously identified the angiogenesis inhibitor angiostatin. Using a similar strategy, we have identified endostatin, an angiogenesis inhibitor produced by ...

  • Angiogenesis Inhibitors

    Treatment with endostatin caused these human tumor masses to shrink in their mouse host. Combined treatment with both angiostatin and endostatin has caused some primary ...

  • Endostatin (Cytokines & Cells Encyclopedia - COPE)

    Cytokines & Cells Online Pathfinder Encyclopedia ... Endostatin. This factor of 20 kDa (185 amino acids) is found in the conditioned medium of the hemangioendothelioma cell line ...

  • BioVendor R&D - Molecules \ Endostatin

    Endostatin . Endostatin is a 20 kDa C-terminal fragment of collagen XVIII. The exact molecular mass determined by ESI-MS was found to be 18 494 Da.Endostatin ...

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