Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index

Definition of «Fatal familial insomnia»

Fatal familial insomnia: Abbreviated FFI. An hereditary prion disease characterized by disrupted sleep (insomnia), motor abnormalities (myoclonus, ataxia, dysarthria, dysphagia, and pyramidal signs), and hyperactivation of the autonomic nervous system. Due to a missense mutation at codon 178 of the prion protein gene on chromosome 20. A sporadic form of fatal insomnia is also known.

For More Information «Fatal familial insomnia»

Comment «Fatal familial insomnia»