Fragile X chromosome: An X chromosome with a heritable fragile site associated with a frequent form of mental retardation -- the fragile X syndrome.
The fragile X chromosome was first sighted by Dr. Herbert A. Lubs in 1969 who termed it the "marker X.". The fragile X is also called FRAXA. It was the first fragile site found on the X chromosome.
The fragile X chromosome is due to a trinucleotide repeat sequence (a recurring motif of 3 bases) in the DNA at that spot.
Males with the premutation will pass it on to all of their daughters and none of their sons (they pass their Y chromosome on to their sons). History of fragile X syndrome
Library > Literature & Language > Dictionary n. An inherited disorder caused by a defective gene on the X-chromosome and causing mental retardation, enlarged testes ...
Fragile X Syndrome Definition. Fragile X syndrome is the most common form of inherited mental retardation. Individuals with this condition have developmental delay ...
Non-profit organization run by parents. Fighting to find a cure for Fragile X Syndrome and helping Fragile X Family's.
In families that exhibit Fragile X, both the number of repeats and the length of the chromosome increase with succeeding generations.