Gene transfer: The insertion of unrelated genetic information in the form of DNA into cells.
There are different reasons to do gene transfer. Perhaps foremost among these reasons is the treatment of diseases using gene transfer to supply patients with therapeutic genes. There are also different ways to transfer genes. Some of these methods involve the use of a vector such as a virus that has been specifically modified so it can take the gene along with it when it enters the cell.
For example, gene transfer may help treat type 1 diabetes (which is due to failure of the pancreas to produce enough insulin). Among the key factors that decide whether the gene for insulin is turned on or off is the gene PDX-1. Using a vector virus the PDX-1 gene has been transferred (into mice) where the gene is expressed by liver cells which now produce insulin. Gene transfer of PDX-1 may reprogram tissues other than the pancreas to make insulin and control the abnormally high blood sugar levels in diabetes.
An overview of information about germline gene transfer research from the July 2002 Ethical Boundaries workshop.
Gene transfer refers to the process of genetic material such as DNA being sent and received among two organisms. There are two types--horizontal and vertical gene ...
Gene transfer: The insertion of unrelated genetic information in the form of DNA into cells. There are different reasons to do gene transfer.
What is Horizontal Gene Transfer? Natural genetic transformation is believed to be the essential mechanism for the attainment of genetic plasticity in many species of ...
Wake Forest researcher receives $369,365 for preclinical testing of gene transfer therapy for myotubular myopathy