Genome, mouse: All of the genetic information contained in the laboratory mouse (Mus musculus).
The genomes of particular nonhuman organisms such as the mouse have been studied for a number of reasons including the need to improve sequencing and analysis techniques. These nonhuman genomes also provide powerful sets of data against which to compare the human genome.
Almost every human gene has a counterpart in the mouse, with similar DNA sequences and basic functions. If the 23 pairs of human chromosomes were broken into smaller blocks, those pieces could be reassembled to produce a serviceable model of the mouse genome.
The mouse genome has some 3,000 million (3 billion) base pairs and is estimated to have at least 50,000 genes . The sequencing of this genome was completed in March 2000.
The mouse has long been a favorite for biomedical research, including serving as a premiere model organism in genetics.
MGI: the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data for researching human health and disease.
NCBI Web Resources: BLAST. Compare your sequence to different mouse-derived sequences. CloneDB. Find clones based on BAC end sequence alignments. dbSNP.
Overview of the effort to sequence the mouse genome, along with a list of additional resources. The effort is supported by NIH and the Wellcome Trust.
A December 2002 press release about the announcement of publication of the mouse genome draft sequence.
Using 600 oligonucleotides with 60 bases each and three enzymes, the authors assemble the entire mouse mitochondrial genome in four isothermal reactions.