Gilbert syndrome: A common, harmless genetic condition in which a liver enzyme essential to the disposal of bilirubin (the chemical that results from the normal breakdown of hemoglobin from red blood cells) is abnormal. The abnormality is caused by a mutation the UDP-glucuronosyltransferase gene.
This enzyme abnormality results in mild elevations of bilirubin pigment in the blood, and the elevated bilirubin pigment can sometimes cause mild yellowing (jaundice) of the eyes.
Gilbert's syndrome is a frequent finding in people in North America and Europe. The condition is usually detected serendipitously (purely by accident) in the course of routine blood screening. People with Gilbert syndrome are otherwise entirely normal with no other signs or symptoms and their liver enzyme levels in blood serum are also entirely normal. Treatment is not necessary.
The condition has also been referred to as constitutional hepatic dysfunction and familial nonhemolytic jaundice.
Includes information on many aspects of the syndrome and its connections to other disorders.
Gilbert's syndrome â€” Comprehensive overview covers causes, complications, self-care of this inherited liver disorder.
Read about Gilbert Syndrome, a genetic condition with symptoms of jaundice. Gilbert syndrome is generally diagnosed after puberty, when sex hormone levels cause the ...
Gilbert syndrome, the most common inherited cause of unconjugated hyperbilirubinemia, was first described by Augustine Gilbert and Pierre Lereboullet in 1901.
a very mild form of jaundice in which there is increased bilirubin in plasma, predominantly in unconjugated form. Usually diagnosed in young adults, it is transmitted ...