Hershey-Chase experiment: An extraordinarily important experiment in 1952 that helped to convince the world that DNA was the genetic material. Alfred Hershey (1908-1997) and his assistant Martha Chase (1923-2003) at the Cold Spring Harbor Laboratory showed that the DNA, not the protein, of the phage virus contains the phage genes. After a phage particle attaches to a bacterium, its DNA enters through a tiny hole while its protein coat remains outside. Key to the success of the experiment was showing that viral infection was unaffected by violent agitation in a kitchen blender (a Waring Blendor) which removed the empty viral protein shells from the bacterial surface. The Hershey-Chase experiment became known as the "blender experiment."
Alfred D. Hershey won a Nobel Prize for his insights into the nature of viruses in 1969, along with Max Delbruck and Salvador Luria. In a 1997 memoriam to Hersey, James Watson wrote that "the Hershey-Chase experiment had a much broader impact than most confirmatory announcements and made me ever more certain that finding the three-dimensional structure of DNA was biology's next important objective. The finding of the double helix by Francis Crick and me came only 11 months after my receipt of a long Hershey letter describing his blender experiment results."
Legend: Illustration of the 1952 experiment connecting DNA and heredity. Side by side experiments are performed with separate bacteriophage (virus) cultures in which either ...
The Hersheyâ€“Chase experiments were a series of experiment. s conducted in 1952 by Alfred Hershey. and Martha Chase, which helped to confirm that DNA
The Hershey and Chase Experiments In 1952 (7 years after Avery's demonstration that genes were DNA), two geneticists: A. D. Hershey and Martha Chase
Experiments that Inspire The Hershey-Chase Experiments (1952) Chris Evers
The Hershey-Chase experiment was a series of experiments conducted in 1952 by Alfred Hershey and Martha Chase that identified DNA to be the genetic material of phages and ...