Nerve growth factor: Abbreviated NGF. A naturally occurring molecule in the body which stimulates the growth and differentiation of the sympathetic and certain sensory nerves. NGF is a protein that consists of 3 types of polypeptide chains -- alpha, beta and gamma -- that interact to form the protein. The NGF beta chain (NGFB) is solely responsible for the nerve growth stimulating activity of NGF. The NGFB gene is in chromosome band 1p22. An ointment containing NGF has been reported to help heal bedsores (decubiti).
A multimeric protein that promotes nerve cell growth and may protect some types of nerve cells from damage, including nerve cells in the cholinergic system.
n. ( Abbr. NGF ) A protein that stimulates the growth of sympathetic and sensory nerve cells.
Abstract. Nerve growth factor (NGF) was discovered 50 years ago as a molecule that promoted the survival and differentiation of sensory and sympathetic neurons.
Nerve growth factor (NGF) is a small secreted protein. that is important for the growth, maintenance, and survival of certain target neurons (nerve cells).
This study is currently enrolling participants. A Phase II clinical study of Ceregene's CERE-110, a gene therapy product designed to deliver nerve growth factor (NGF) to ...