New England Journal of Medicine: Despite its regional name, The New England Journal of Medicine (NEJM) is far from provincial. It is an eminent weekly national and international general medical journal, devoted to no single specialty, but to all of medicine. The Journal is published by the Massachusetts Medical Society and is closely associated with the medical schools (Boston University, Harvard and Tufts) in the Boston area.
By North American standards, it is a venerable journal. The first issue of The New England Journal of Medicine appeared in January of 1812. The Original Papers in that inaugural issue were titled as follows (verbatim):
In case you are curious, Bichat was Marie F.X. Bichat, a French anatomist, physician, and biologist (1771-1802) after whom Bichat's canal, Bichat's fat-pad, Bichat's fissure, Bichat's foramen, Bichat's fossa, Bichat's ligament, Bichat's membrane, Bichat's protuberance, and Bichat's tunic were named.
That was, indeed, the way they spelled "research" in 1812 (at least in The New England Journal) -- "researche."
And the paper about "Spurred Rye" had to do with ergot and its powers "ad partum accelerandum." Ergot is a product of a parasitic fungus of rye grass that induces uterine contractions. The Journal quite rightly observed that "it has hastened the termination of the labour."
A searchable medical index of content since 1812 from the New England Journal of Medicine.
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Journal's description: The New England Journal of Medicine (N Engl J Med or NEJM) is a peer-reviewed medical journal published by the Massachusetts Medical Society.