Nipah virus: A virus that infects pigs and people in whom it causes a sometimes fatal form of viral encephalitis (brain inflammation). Nipah is the name of the first village the virus struck near Kuala Lumpur in Malaysia. The Nipah virus is similar to Hendra virus that was discovered in Australia in 1994. Nipah virus caused a severe outbreak of viral encephalitis in Malaysia in 1998 - 1999.
The main risk factor for infection is recent contact with pigs. Most patients have had direct contact with pigs in the two weeks preceding the onset of the illness -- fever, headache, dizziness and vomiting. The infection may spread to people through contact with pig secretions such as feces or saliva or through contact with infected dogs.
The spread of the Nipah virus illustrates a problem due to trends in livestock production -- large-scale production and international commerce. Huge hog farms can have tens of thousands of animals. Some infectious agents such as the Nipah virus are associated with intensity of production and concentration of animals in limited spaces. International commerce in meat and poultry now increases the chance of the worldwide dissemination of exotic infectious agents like the Nipah virus.
Bats are believed to be the natural host of Nipah virus. The virus is similar but not identical to Hendra virus, another agent of zoonotic viral disease in which bats are the usual host.
KEY FACTS. Nipah virus causes severe illness characterized by inflammation of the brain (encephalitis) or respiratory diseases. Nipah virus can be transmitted to humans ...
Nipah virus electron micrograph Image courtesy of C.S. Goldsmith and P.E. Rollin (CDC), and K.B. Chua (Malaysia).
Nipah Virus. Agent Hosts Epidemiology Nipah As a Biological Weapon Clinical Features Laboratory Diagnosis Treatment Prevention and Control Public Health Issues
Article describes Nipah virus, its symptoms, diagnosis, and treatment, and describes outbreaks of the virus that have occurred.
From September, 1998 and through early 1999, at least 265 people in Malaysia developed febrile encephalitis and 111 people died. Although initially attributed entirely ...