Nocturia: Excessive urinating at night. People with nocturia must get up, often two times or more, during the night to urinate. Normally, urine is more concentrated at night and is produced in lower amounts, so that uninterrupted sleep is possible. However, excess urine production at night can occur due to a number of conditions including diabetes, urinary tract infection, bladder infection, kidney failure, prostatic hyperplasia, taking certain medications, or sleep disorders. Treatment of nocturia is dependent upon the underlying cause.