Warfarin: An anticoagulant drug (brand names: Coumarin, Panwarfin, Sofarin) taken to prevent the blood from clotting and to treat blood clots and overly thick blood. Warfarin is also used to reduce the risk of clots causing strokes or heart attacks.
Warfarin works by suppressing the production of some clotting factors (interfering with prothrombin activation) and thereby inhibiting the clotting of blood.
Warfarin interacts with many other drugs, including some vitamins. These interactions can be dangerous, even life-threatening. If you are taking Warfarin, talk to your doctor before taking any other prescription or over-the-counter medications.
University of Wisconsin biochemistry professor Karl Paul Link and his co-workers first isolated dicoumarin, a molecule in spoiled sweet clover that causes cattle to hemorrhage and die. The discovery led to the synthesis of Dicumarol, the first anticoagulant drug that could be taken orally. The successor to Dicumarol was Warfarin.
Warfarin is named after WARF, the Wisconsin Alumni Research Foundation, to which Professor Link assigned the patent. Warfarin was originally marketed as a rodenticide (the rats bleed to death). Its effectiveness in controlling pestilent rats and mice led to great commercial success. Warfarin has, in addition, become the most widely prescribed anticoagulant drug for people and saved countless lives.
Library > Literature & Language > Dictionary ( wÃ´r ' fÉ™r-Än ) n. A white crystalline compound, C 19 H 16 O 4 , used as a rodenticide and as an ...
Warning. Warfarin may cause severe bleeding that can be life-threatening and even cause death. Tell your doctor if you have or have ever had a blood or bleeding ...
Accurate, FDA approved Warfarin information for healthcare professionals and patients - brought to you by Drugs.com.
Warfarin is an anticoagulant used to to prevent heart attacks, strokes, and blood clots. Includes warfarin side effects, interactions and indications.
Warfarin may cause severe bleeding that can be life-threatening and even cause death. Tell your doctor if you have or have ever had a blood or bleeding ...