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Drugs reference index «Integrilin»



Generic Name: Eptifibatide (ep-ti-FIB-ih-tide)Brand Name: Integrilin

Integrilin is used for:

Treating unstable angina (chest pain) or certain types of heart attacks. It may also be used to treat patients undergoing a certain type of procedure (percutaneous coronary intervention [PCI]). It may also be used to treat certain conditions as determined by your doctor that may not be listed in the professional package insert.

Integrilin is a platelet aggregation inhibitor. It works by preventing blood platelets from sticking together and forming blood clots.

Do NOT use Integrilin if:

  • you are allergic to any ingredient in Integrilin
  • you have a history of bleeding problems, active bleeding within the past 30 days, stroke or bleeding in the brain, or major surgery or severe injury within the past 6 weeks
  • you have uncontrolled severe high blood pressure or if you must have kidney dialysis
  • you are or will be taking another medicine similar to this one

Contact your doctor or health care provider right away if any of these apply to you.

Before using Integrilin :

Some medical conditions may interact with Integrilin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems or high serum creatinine levels, high blood pressure, or low blood platelet levels (eg, thrombocytopenia)

Some MEDICINES MAY INTERACT with Integrilin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin, heparin), aspirin, dipyridamole, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), or thrombolytics (eg, alteplase) because risk of bleeding may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Integrilin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Integrilin :

Use Integrilin as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

  • Integrilin will be administered as an injection at a hospital. Ask your doctor any questions that you may have about Integrilin .
  • If you miss a dose of Integrilin , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Integrilin .

Important safety information:

  • Integrilin may reduce the number of blood cells that are needed for clotting. To prevent bleeding, avoid situations where bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark tarry stools to your doctor.
  • After using Integrilin , your doctor may prescribe other medicines to continue your treatment at home. If so, be sure to fill your prescriptions promptly.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Integrilin .
  • LAB TESTS, including platelet counts, blood cell counts, and serum creatinine levels, will be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
  • Use Integrilin with caution in the ELDERLY because they may be more sensitive to its effects, especially the risk of bleeding.
  • Integrilin is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Integrilin during pregnancy. It is unknown if Integrilin is excreted in breast milk. If you are or will be breast-feeding while you are using Integrilin , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Integrilin :

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; bleeding from gums when brushing or flossing teeth; coughing up blood; excessive bleeding from cuts; increased menstrual bleeding; major bleeding episodes; nosebleeds; one-sided weakness; red urine; redness or pain after an injection; severe headache; stomach pain or swelling; unexplained vaginal bleeding; unusual bruising; vision or speech changes; vomiting blood or material that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Integrilin :

Vials should be stored refrigerated at 36 to 46 degrees F (2 to 8 degrees C). Protect from light until time of use. Vials may be stored at room temperature between 59 and 86 degrees F (15 and 30 degrees C) for a period of 2 months or less. Do not use past the expiration date. Discard any unused portion left in the vial. Keep Integrilin out of the reach of children and away from pets.

General information:

  • If you have any questions about Integrilin , please talk with your doctor, pharmacist, or other health care provider.
  • Integrilin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Integrilin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Integrilin Consumer Overview
  • Integrilin Prescribing Information (FDA)
  • Eptifibatide Professional Patient Advice (Wolters Kluwer)

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