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Drugs reference index «Wilate»



Generic Name: Antihemophilic Factor/von Willebrand Factor (AN-tee-HEE-moe-FIL-ik FAK-tor/von WILL-a-brand FAK-tor)Brand Name: Wilate

Wilate is used for:

Treating bleeding episodes in certain patients with von Willebrand disease.

Wilate is a human clotting factor complex prepared from pooled human plasma. It works by increasing the amount of clotting factor VIII and von Willebrand factor in the blood. This helps the blood to clot properly, which helps to stop bleeding.

Do NOT use Wilate if:

  • you are allergic to any ingredient in Wilate
  • you have had a severe allergic reaction (eg, rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue) to other medicines that contain antihemophilic factor or von Willebrand factor or other medicines derived from human plasma

Contact your doctor or health care provider right away if any of these apply to you.

Before using Wilate :

Some medical conditions may interact with Wilate . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood clots in the legs, lungs, or eye, or if you are at risk for developing blood clots

Some MEDICINES MAY INTERACT with Wilate . However, no specific interactions with Wilate are known at this time.

Ask your health care provider if Wilate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Wilate :

Use Wilate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Wilate is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Wilate at home, a health care provider will teach you how to use it. Be sure you understand how to use Wilate . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do NOT shake Wilate .
  • Do not use Wilate if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Use Wilate immediately after mixing.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Wilate , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Wilate .

Important safety information:

  • Wilate may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Wilate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Wilate comes from human blood. Rarely, patients receiving products that come from human blood have developed certain viral infections (eg, parvovirus B19, hepatitis A). Discuss any questions or concerns with your doctor. Contact your doctor if you develop symptoms such as fever, rash, joint aches or pain, loss of appetite, nausea, vomiting, unusual tiredness, or yellowing of the eyes or skin.
  • Discuss with your doctor whether you should receive a hepatitis A and hepatitis B vaccine.
  • Patients receiving clotting factors sometimes develop antibodies or inhibitors to the medicine. This makes it less effective. If Wilate stops working or does not work as well as it has before, contact your doctor immediately for instructions.
  • Patients receiving products that come from human blood have a very rare risk of developing a central nervous system disease called Creutzfeldt-Jakob disease. Discuss any questions or concerns with your doctor.
  • Tell your doctor or dentist that you take Wilate before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including blood clotting, blood hematocrit levels, factor VIII levels, or von Willebrand factor levels, may be performed while you use Wilate . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: It is not known if Wilate can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Wilate while you are pregnant. It is not known if Wilate is found in breast milk. If you are or will be breast-feeding while you use Wilate , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Wilate :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; mild itching, burning, or stinging at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); calf pain, swelling, or tenderness; chest pain; coughing up blood; dark urine; fainting; fast heartbeat; fever or chills; flushing; nausea; new or worsening bruising or bleeding; restlessness; severe or persistent dizziness or headache; shortness of breath; sluggishness; tingling; unusual weakness or fatigue; vomiting; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Wilate :

Store Wilate in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Wilate may also be stored at room temperature, below 77 degrees F (25 degrees C), for up to 6 months. Store away from heat and light. Do not return Wilate to the refrigerator once it has been stored at room temperature. Do not refrigerate after mixing. Keep Wilate out of the reach of children and away from pets.

General information:

  • If you have any questions about Wilate , please talk with your doctor, pharmacist, or other health care provider.
  • Wilate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Wilate . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider

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